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What is the next step in management of a thyroid nodule that was biopsied and classified as Bethesda III, but Afirma genetic testing reveals parathyroid signature?

Patient does not have hypercalcemia.
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Do you routinely review calcium levels in patients with thyroid nodules prior to FNA?

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2 Answers
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Endocrinology · University of Utah
Answered on

This is not an uncommon clinical presentation of intrathyroidal parathyroid adenomas, diagnosed incidentally on molecular profiling of cytological indeterminate nodules (CIN). These adenomas most often have the imaging features of a TIRADS 4 thyroid nodule (with well-demarcated margins, solid, profo...

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Mednet Member
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Endocrinology · Johns Hopkins Outpatient Endocrinology
Answered on

Would also check PTH levels, of course.

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