What is the optimal intrathecal chemotherapy regimen for leptomeningeal carcinomatosis from breast cancer?
What schedule do you use?
1 Answer
Mednet MemberInvited Expert
Medical Oncology · H Lee Moffitt Cancer Center, University of South Florida
Answered on
For HER2- disease, we tend to do IT methotrexate or topotecan. For HER2+ disease, we routinely do IT Herceptin plus systemic treatments with a TKI like lapatinib with excellent long term control in some patients.
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