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What is the optimal sequencing for SBRT boosts in prostate cancer?

Should the boost be delivered before or after EXBRT? What is the ideal delay (if any) between the two?
1 Answer
Mednet Member
Mednet Member
Radiation Oncology · Mallory Radiotherapy, PLLC
Answered on

I prefer to follow the schedule used on the PROMETHEUS trial (prospective, phase 2) and have had good results.

Wegener et al., PMID 38302321

This protocol delivered an upfront 2-fraction SBRT boost with each fraction given 1 week apart. The EBRT component (46 Gy in 23 fractions) was then delivered 2...

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