What is the optimal therapy for laryngeal candidiasis in pregnancy?

Thirty years ago, I was consulted on a woman in her 30s with candidemia after fetal demise from Candida chorioamnionitis. During the pregnancy, she had been treated several times with clotrimazole for Candida vaginitis. Given that repeated exposure, I guessed that her Candida isolate would be azole-...

Fluconazole is directly contraindicated in the first trimester; it is low risk in the later trimesters, but the issue at play here is prolonged exposure to treat laryngeal candidiasis--which would be contraindicated, as it would impact fetal growth, particularly around hormonal system development (I...