What is the practical application of alpha-synuclein seed amplication assay CSF testing for the diagnosis and management of Parkinson's disease?
In light of commercially available SYNTap CSF testing.
Answer from: at Academic Institution
The α-synuclein seed amplification assay (αSyn-SAA) sensitively identifies patients with Parkinson’s disease from cerebrospinal fluid (CSF) samples. A positive αSyn-SAA is proposed to "biologically define" Parkinson’s disease and anchor disease staging. A positive &alph...