What is the radiation volume for M+ pure germinoma with brain only extra-ventricular mets and negative CSF/spine imaging?
1 Answers
Mednet Member
Radiation Oncology · St Jude Children's Research Hospital
In general, I wouldn't recommend chemo for M+ Germinoma kids because it does not favorably improve the therapeutic ratio based on the findings from GCT96 (NCT00293358).
Independent of chemo, 24 Gy CSI with a boost to 36-40Gy is sufficient for cure.
With chemo, 21 Gy CSI & an involved field boost to 3...