What is the role for RNI in a postmenopausal female with clinically N+, hormone receptor positive breast cancer s/p lumpectomy and ALND with low volume nodal disease (e.g., 1/12 nodes positive)?

When thinking about low volume nodal disease in cN+ patients, I tend to think about MA20 which included patients undergoing an ALND and 85% had 1-3 LN involved. I will offer these patients adjuvant RT to the breast and RNI (SCV/axilla with consideration of IM nodes based on dosimetry) based on the i...

Whether a patient is clinically node negative or node positive is sometimes more related to the extent of the workup performed, rather than inherent differences in biology/prognosis. For instance, a women who has a breast MRI which picks up a small level I axillary LN that is subsequently biopsied (...

I think @Dr. First Last and @Dr. First Last are a little too reticent in their recommendation for RNI in a patient with 1 positive axillary node. In addition to the data cited from MA-20 one should consider all the PMRT data which has convincingly demonstrated the value of RT for pts with 1-3 pos ax...