What is the role of adjuvant radiation for gastric cancer found to be locally advanced after up-front surgery in the setting of <D2 but R0 resection?

I think one has to be very careful making blanket statements regarding management of the type of tumor described. The only real data supporting the standard use of RT in virtually all of these patients was the Macdonald trial from a couple of decades ago (and the patients were often treated three de...

For patients who have not received preoperative chemotherapy or chemoradiation therapy, following an R0 resection but a < D2 lymph node dissection, postoperative chemoradiation should be recommended for patients with pT3-T4, any pN tumors or any pT, pN+ tumors. Selected patients with pT2, pN0 tumors...