What is the role of anticoagulation in patients with septic thrombophlebitis?
Would you be comfortable with the use of DOACs?
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Do you anticoagulate patients with septic thrombophlebitis?
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1 Answer
Mednet MemberInvited Expert
Hematology · Mayo Clinic
Answered on
The role of heparin anticoagulation in septic thrombophlebitis is controversial. There are limited to no randomized trials to document outcomes. A systematic review (Falagas et al., PMID 17222406) supported this practice, and the Infectious Disease Society also supports this practice. The role of oral direct-acting anticoagulants (DOACs) is even less well studied. An individualized approach to each situation is important. If there are clinical indications for ongoing anticoagulation after the acute event, in the absence of contraindications, continue with a DOAC for a limited time interval.