What is the role of GammaTile in the management of primary brain tumors and brain metastases?

Topics: Radiation Oncology • Neuro-Oncology

Is there sufficient data to justify the routine use of GammaTile in the treatment of primary CNS malignancy or brain metastases?

Answer from: Radiation Oncologist at Academic Institution

GammaTiles are an intracranial brachytherapy product marketed by GT Medical Technologies consisting of a Cs-131 source imbedded within a collagen matrix. Proponents of the technology argue that advantages of GammaTiles over external beam radiotherapy techniques include the ability to “start&rd...

Comments

Radiation Oncologist at Phoenix CyberKnife and Radiation Oncology Center
Dr. @Wilke's summary is concise. I would add that ...

Answer from: at Academic Institution

While surgically targeted radiotherapy (STaRT) implants may have a role in the delivery of adjuvant radiation following surgical resection, no specific delivery modality should be considered "routine". Post-operative SRS, along with pre-operative SRS, STaRT, and low-energy X-ray intraoperative radio...

Answer from: Radiation Oncologist at Community Practice

In the setting of de-novo brain metastases, assuming the patient will go on to full-dose chemotherapy, possibly with immunotherapy (i.e. carbo/pem/pem if lung cancer). Given that the half-life of Cs131 is 9.2 days, how long would one wait after implant before administering full-dose chemotherapy?&nb...

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