What is the target ferritin level for patients with hereditary hemochromatosis and signs of end-organ damage?

I believe the best marker to guide phlebotomy therapy for iron overload is the serum ferritin concentration. I use a target ferritin level of approximately 50 ng/ml. However, one could justify a ferritin level of <200 ng/ml from the literature of serum ferritin compared to body iron stores in HFE he...

Treatment should be initiated in C282Y homozygotes with an elevated SF, defined as >300 ng/mL in men and >200 ng/mL in women, along with a TS of ≥ 45%.

Phlebotomy should be done weekly with monitoring serum ferritin every 4 weeks till serum ferritin is <200 ng/ml.

Then continue weekly phlebotomy with ...