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What is the timing of onset of alectinib induced ILD, and is there any correlation between dose and the occurrence of ILD?

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Medical Oncology · Roswell Park Comprehensive Cancer Center

There is wide variability in the timing of onset of ALK TKI-induced ILD. In a single-institution retrospective analysis published by Koshikawa et al., PMID 32237210, onset specifically of alectinib-induced ILD ranged from day 9 to 531. Risk of ALK TKI-induced ILD was associated with older age and wo...

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