What is your approach to a patient with positive antiphospholipid antibodies who otherwise do not meet clinical criteria for APS?

As antiphospholipid antibodies constitute a diagnostic criterion of SLE, such patients may need to be evaluated and monitored long term for both SLE and APS.

Agree with Drs. @Dr. First Last and @Dr. First Last. To expand, women who have APLAs should avoid estrogen replacement and estrogen containing contraceptives. Progestin only contraception is preferred although, I/we generally recommend avoiding third generation progestins as these may increase the r...

Agree with the above.

In addition, improving modifiable risk factors for thrombosis is key for primary prevention in these patients (obesity, lipids, smoking, hypertension). Women with the high risk Ab profiles should be advised about the risk of oral contraceptives. Patients need to be aware of the...