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What is your approach to differentiating Randall plaques from actual small non-obstructing stones when reviewing imaging testing for your patients with recurrent nephrolithiasis?

2 Answers
Mednet Member
Mednet Member
Nephrology · University of Chicago Medicine

In truth, I almost never can tell with present CT imaging. Once we have a URS with images, it is easier in a given case. Even more misleading is plugging, which can be dense looking on CT and essentially in tissues and not amenable to removal, now requiring surgery. Specialized, very high-resolution...

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Mednet Member
Mednet Member
Nephrology · Mayo Clinic

Randall‘s plaque represents subepithelial deposits of calcium phosphate in the renal papillae. They typically serve as a nidus for calcium oxalate stones.

Differentiating the two radiographically is challenging. However, they have common risk factors: hypercalciuria and low urine volume.

My approach...

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