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What is your approach to DVT prophylaxis in patients who require IVIG but are at increased risk for thrombotic events?

E.g., a patient with newly diagnosed CIDP who is wheelchair-bound.
2 Answers
Mednet Member
Mednet MemberInvited Expert
Neurology · University of Minnesota
Answered on

I am unaware of any published data to guide the decision-making for this topic. Empirically, I recommend low-dose aspirin in patients >50 who have to get long-term IVIG especially if there are a lot of underlying risk factors for thrombosis like diabetes, immobility, etc. Again, this is not an evide...

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Mednet Member
Mednet MemberInvited Expert
Neurology · Cedars-Sinai Medical Center
Answered on

There's not much available literature on this, but the risk is probably related to peak dosing. I couldn’t find a report of thrombosis with SCIg, but the warning is there and the risk must be very low. So, I would use SCIg when I can. Otherwise, my approach is to spread the treatment out; lower dose...

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