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Primary Care • General Primary Care
What is your approach to isolated alkaline phosphatase without other laboratory abnormalities?
What are your next diagnostic steps/tests?
Answer from: at Academic Institution
Assuming none of the other LFTs are abnormal, I would get a GGT.
If GGT is elevated --> likely a hepatobiliary issue. Would consider age, medical history, and risk factors. If persistently elevated, could consider RUQ US + MRCP. Conditions like PSC or PBC are frequently discovered due to asympto...
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