What is your approach to managing Grover's Disease (Transient Acantholytic Dermatosis) that has failed topical steroids?
What is your preferred treatment approach for managing refractory Grover's Disease (Transient Acantholytic Dermatosis)?
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I'm a big fan of low-dose naltrexone for Grover's Disease (and Hailey-Hailey and Darier's Disease). It's a safe and effective treatment that I've seen work very well. The dose ranges between 1-5mg daily. It seems like 3mg is often the sweet spot. Patients sometimes report more trouble sleeping and/o...
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Oral minocycline or doxycycline can help along with topical calcipotriene. Nb-UVB can also work for grovers if patients have access to treatment.
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IM Kenalog q 3-4 months.
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For resistant persistent cases, Dupilumab has been effective and pretty safe.
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