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What is your approach to using intraperitoneal sodium thiosulfate for a patient with ESKD on peritoneal dialysis who develops calciphylaxis?

2 Answers
Mednet Member
Mednet Member
Nephrology · Renal Associates Pa

I believe if the patient has calciphylaxis, PD should not be continued, and more efficient IHD or HHD with the addition of sodium thiosulfate is better.

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Mednet Member
Mednet Member
Nephrology · UCHealth University of Colorado Hospital (UCH)

I see no reason not to continue PD while using sodium thiosulfate. Though intraperitoneal administration of sodium thiosulfate may cause chemical peritonitis, the drug often can be administered successfully via this route (see Teh & Renaud, PMID 37131321). And even if IP administration does result i...

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