What is your dose-fractionation for cylinder-based vaginal cuff HDR brachytherapy for an isolated vaginal cuff recurrence after whole pelvis EBRT with residual thickness of disease <5 mm?
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2 AnswersMednet Member
Radiation Oncology · Varian Medical Systems/Allegheny health network
I usually prescribe 5Gy x5.
I don't prescribe to a fixed thickness but treat based on residual thickness seen on MRI using multichannel applicator.
I lesion at apex then treat upper 2-3 cm of vagina
Here is out paper describing technique and outcome in detail
Mednet Member
Radiation Oncology · Washington University School of Medicine
In tha past we usually prescribed at 0.5 cm depth LDR or HDR biologically equivalent doses. As we have evolved to image-guided BT, I agree with @Dr. First Last's answer and @Dr. First Last's paper recommendation