What is your experience with using Frailty Index or other geriatric screening in making decisions for elderly patients with multiple myeloma?
Frailty Index per Palumbo et al. PMID 25628469
Is it practical to apply in clinics? Have you made decision changes based on it?
2 Answers
Mednet MemberInvited Expert
Medical Oncology · Winship Cancer Institute of Emory University
Answered on
The IMWG frailty score is the most comprehensive score developed to date. While predictive, trials testing its value prospectively are ongoing. Linking age, comorbidities (Charlson), and functional scales (ADL & IADL) makes great logical sense. I don't use it.
The UKMRA Myeloma XIV FiTNEss [Frailty-...
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Mednet MemberInvited Expert
Medical Oncology · University of Washington, Fred Hutchinson Cancer Research Center
Answered on · Updated on
I completely agree with everything @Dr. First Last said, in particular, the details of lenalidomide and dexamethasone (including that wonderful trial by Larocca et al., PMID 33739404!)
At our center, we don't routinely use the IMWG frailty index for predictable reasons - not implemented into workflow...
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