What is your frontline treatment of choice for patients with systemic and secondary CNS involvement by DLBCL?
1 Answers
Mednet Member
Medical Oncology · University of Maryland Cancer Center
It depends on the intent of treatment, the age, and the PS of the patient. If you are going for a potential curative intent, R-CHOP combined with high-dose methotrexate (R-CHOP-M) - Damaj et al., PMID 26185174, followed by thiotepa-based (thiotepa-BCNU) autoSCT in young, fit patients with chemorespo...