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What is your preferred adjuvant treatment for surgically staged IB dedifferentiated endometrial carcinoma, with negative SLNBx and extensive LVSI?

Would you consider chemoRT or carbo/taxol/immunotherapy?
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What adjuvant treatment would you offer a patient with surgically staged IB dedifferentiated endometrial adenocarcinoma with extensive LVSI?

20 physicians have voted

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2 Answers
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Gynecologic Oncology · VA Boston Healthcare System
Answered on

Depends on how much LVS is involved.

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Radiation Oncology · Vanderbilt-Ingram Cancer Center
Answered on

We would generally recommend chemotherapy at a minimum for a dedifferentiated uterine carcinoma, although approval of immunotherapy is unlikely to be obtained given IT was not studied in any stage I patients, even for high-risk histologies.

As a radiation oncologist, for IB high-risk histologies case...

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