Would you recommend adjuvant chemotherapy for a patient with serous endometrial cancer initially treated with neoadjuvant radiation due to cervical involvement precluding surgical resection who is now s/p hysterectomy/BSO/LND/omentectomy with only small amount of residual disease confined to the endometrium?

Yes, assuming adequate performance status and no contraindications, I would recommend adjuvant postoperative chemotherapy for any patient requiring neoadjuvant treatment with uterine serous carcinoma that has any residual disease found at the time of hysterectomy.

For the patient in this case, she in...

Definitely.