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What is your preferred CSI dose/fractionation for leptomeningeal disseminated low-grade glioma?

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Mednet Member
Mednet Member
Radiation Oncology · University of Arizona

When treating leptomeningeal dissemination (LMD) of low-grade glioma (LGG) with craniospinal irradiation (CSI), radiation doses vary depending on the patient's age and clinical situation. While definitive dosing is still being investigated, established ranges from clinical practice and studies provi...

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Mednet Member
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Radiation Oncology · Fox Chase Cancer Center

That's a tough one. I doubt it's low grade anymore. I think 30-36 Gy 1.8 Gy fractions and a boost to bulky disease to 54, assuming they've not had RT before. Agree with protons if available, or VMAT.

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