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What is your preferred first line treatment approach for a patient with PDL-1 high (>50%) NSCLC presenting with CNS mets?

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Mednet Member
Mednet Member
Medical Oncology · Karmanos Cancer Institute, Wayne State University

The treatment decision and sequencing in patients with brain metastasis from non-oligometastatic NSCLC with high PD-L1 expression and no traditional actionable genomic alterations depend on size and location of brain mets as well as associated symptoms.

Based on data from several prospective and retr...

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Mednet Member
Mednet Member
Medical Oncology · University of Colorado Cancer Center
Pembrolizumab, if asymptomatic. SBRT in addition, if symptomatic.

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