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What neoadjuvant chemotherapy would you consider for squamous cell carcinoma arising from a ruptured tailgut cyst?

Would you extrapolate treatment from the paradigm of anal SCC?
1 Answer
Mednet Member
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Medical Oncology · Indiana University Melvin and Bren Simon Cancer Center
Answered on

Tailgut cysts are congenital lesions that develop from tailgut embryonic remnants. Though malignant transformation has been described, literature is largely limited to case reports. I would ensure the patient has been adequately staged with PET/CT and/or MRI of the pelvis. If resectable, I would adv...

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