What radiation approach do you prefer when using total neoadjuvant therapy for rectal cancer with extensive anal sphincter or pelvic floor involvement?

Topics: Radiation Oncology • Gastrointestinal Cancers

Do you treat the inguinal lymph nodes prophylactically when using RAPIDO-style total neoadjuvant therapy (25 Gy in 5 fractions followed by CAPOX or FOLFOX chemotherapy)?

Answer from: Radiation Oncologist at Academic Institution

Yes, the inguinal nodes should be treated and no, it should not be with short course. When the anal canal has to be treated, it is best to use long course chemo radiation because the following surgery the long-term bowel function is better according to patient reported outcomes from the UK national ...

Comments

Radiation Oncologist at University of Utah School of Medicine
If the patient will have an APR, then I guess the ...

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