What radiation dose would you use to treat a symptomatic osseous lesion secondary to AL-amyloidosis?
2 Answers
Mednet Member
Radiation Oncology · Boston Medical Center, Boston University School of Medicine
Answered on · Updated on
Extrapolating from our tracheobronchial experience, we’ve used 20 Gy in 10 fractions to target the underlying plasma cells that produce amyloid production. We’ve also used this regimen for ocular and GU (ureteric and bladder) amyloidosis. If there are obstructive or symptomatic lesions, then surgica...
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Mednet MemberInvited Expert
Radiation Oncology · Medical University of South Carolina (Charleston)
Answered on
20 Gy in 10 fractions. I refer you to this PRO article that I co-authored with colleagues at UNC.
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