What strategies do you use for patients on medications for ADHD who experience afternoon rebound/withdrawal?   

There are several strategies to try. The first thing I do to address withdrawal dysphoria is usually a high-protein snack about 30 minutes before the symptoms are typically noted. In most of my pediatric patients, this is a game-changer. If that's not helpful, you can consider using a short-acting s...

Use a longer-acting formulation, and may have to increase the dose of stimulant. May use alpha-2 agonists earlier if necessary.

For the few patients where this happens, I may try to use a different long-acting agent, or I may add in a short-acting small dose for rescue in the afternoon.