What stroke symptoms would lead you to avoid using oxaliplatin in a patient with metastatic colon cancer and a recent stroke?

This is not a rare situation, given colorectal cancer in general is a disease with a median age of 66 in men and 69 in women at diagnosis. If the patient is considered to be a good candidate for systemic therapy, which means the patient must recover from the recent stroke reasonably well with well-preserved performance status, there is no contraindication for oxaliplatin. Oxalipatin can lead to stroke-like symptoms (which is different from a true stroke) in very few patients with only a handful ...