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Topics:
Gynecologic Cancers
•
Ovarian Cancer
What toxicities related to mirvetuximab have you seen in your patients and how have you managed them?
In particular, have you seen dose-limiting diarrhea, ocular toxicities or infusion reactions?
Related Questions
Would you ever re-treat recurrent ovarian cancer with mirvetuximab soravtansine if the patient responded to it in the past (e.g., more than 6 months ago)?
How have you incorporated mirvetuximab into the treatment of platinum-resistant ovarian cancer?
Do you routinely use prophylactic anticoagulation when treating ovarian cancer patients with neoadjuvant chemotherapy?
Has your preferred adjuvant treatment for IC mucinous ovarian cancer changed in response to the platinum chemotherapy shortage?
Do you routinely give prophylactic antibiotics/steroids for patients on MEK-inhibitors (e.g., trametinib) to prevent rash/dermatitis?
How do you counsel patients with homologous recombination repair proficient tumors already on niraparib maintenance therapy, prior to the FDA restriction?
Do you test ovarian cancer tumors for targetable biomarkers (e.g., HER2, folate receptor, MMR) at the time of primary diagnosis or at time of recurrence?
Would you prescribe vaginal estrogen cream for vaginal dryness to a patient in her 40s with a history of stage IA granulosa cell tumor?
Do you personally review all imaging you order or rely judiciously on radiologist interpretation?
In a patient with an HR-proficient stage III high-grade serous ovarian cancer s/p R0 primary debulking surgery for whom you are not considering bevacizumab in addition to chemotherapy, would you consider IP chemotherapy?