If the patient was responding to treatment but maybe presented with a large mass and had an insufficient response to chemo to convert her to resectability, further chemotherapy with carboplatin, preferably in combination with another agent - and I wouldn't rule out using docetaxel, given the activit...

We had a trial of platinum in combination with radiation therapy in this situation to improve local response. She may be eligible for clinical trials of novel treatments.

It depends on the clinical scenario. I am assuming that this question is based on that, with one more push of the response, the patient can be a candidate for local therapy. In this situation, I usually like to use gemcitabine and carboplatin, which provide a platinum-containing regimen. Most patien...

I defer to my colleagues, more knowledgeable in Medical Oncology, regarding systemic therapy options for this patient. Obviously, she is a prime candidate for breast and regional nodal irradiation. The breast dose will depend on the final tumor response and possible eligibility for a mastectomy (pre...