What treatment would you offer to a patient after resection of a solitary metastatic melanoma from the brain without evidence of other sites of disease?

Resected stage IV melanoma, including patients with resected brain metastases, was included in the CHECKMATE 238 study of adjuvant nivolumab vs. adjuvant ipi published by Weber et al in NEJM 2017, which was a positive study overall with improved RFS in the nivolumab arm. The magnitude of effect in t...