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What treatment would you recommend to a patient with a locally recurrent sarcoma of the retrohepatic IVC (reconstruction of IVC with PTFE graft) resected over 2 years ago?

This was resected over 2 years ago with reconstruction of the IVC with a PTFE graft. No preop or postop RT given and the recurrence is in the area where there was a positive margin. Patient has a good performance status and is not a candidate for chemo with Hx of AML s/p BMT 20 years ago and didn't tolerate postop chemo. If you recommend radiation what is the dose and fractionation?
1 Answer
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Radiation Oncology · The Ohio State University - James Cancer Hospital and Solove Research Institute
Answered on · Updated on

I would want to know histology, grade, and size.

Most caval tumors are leiomyosarcoma. Local recurrence is rare for retroperitoneal LMS. But it can happen, especially as here with an untreated positive margin.

If resectable, I would recommend surgery and RT to standard STS doses. The standard timi...

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