What workup do you consider necessary for “medical clearance” when patients present to the emergency department with altered mental status and possible psychiatric illness?

In the emergency room, whenever there is a question of altered mental status, we request UA+UTOX, CBC, CMP incl. LFTs, thyroid panel, B12, folate, b-HCG if applicable, and any related plasma medication levels +EKG. Based on a patient's substance use history or medical history, we might order additio...

CMP (not BMP), CBC, UA, and drug screen for most.