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What workup do you perform for elevated B12 levels in an adult who is not taking supplements?

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Mednet Member
Mednet Member
Hematology · Weill Cornell Medical College and Houston Methodist Hospital

There is no convincing evidence of the harmful effects of elevated serum B12 per se, so I have not vigorously pursued this lab finding. If excessive supplements are consumed, B12 is innocuously excreted in the urine once tissue receptors are saturated. Nonetheless, this question raises some interest...

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