What would be the right patient profile and experience for someone who may have (operational) tolerance and how do you approach immunosuppresison management (or withdrawal) in this patient?  

We try our very best to minimize immunosuppression (IS) in all patients. A very small subset of patients post-liver transplant (LT) can stop all IS, unlike other solid organ transplants. We don't actively discontinue all IS in patients, but have several patients who have done so on their own, remain...