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What would be your advice to providers who are wary of QTc prolongation after starting an amiodarone load and wish to discontinue it?

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2 Answers
Mednet Member
Mednet Member
Cardiology · NorthShore University HealthSystem

Amiodarone has been studied in patients with prior TDP patients and found to be safe (small paper from Mattioni et al., PMID 2774388 at Northwestern at the time of my EP fellowship). Amiodarone has been found to be more effective when it prolongs the QT, and the 500 mS limit does not apply to it as ...

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Mednet Member
Mednet Member
Cardiology · Lankenau Heart Group

No need to worry about QT prolongation with amiodarone. TdeP is a rare event with this drug and not predictable by QT interval alone.

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