What would be your choice and duration of adjuvant therapy for a perforated MSI-H stage II (T4N0) colon cancer?
Is there a change in approach over the past few years? Would there be a role for the 12-gene recurrence score?
1 Answer
Mednet MemberInvited Expert
Medical Oncology · Dana-Farber Cancer Institute
Answered on
There are no data of which I am aware which directly address this situation. Although patients with stage II MSI-H tumors generally have an extremely favorable prognosis, the perforation is worrisome. I would not be opposed to giving six months of adjuvant FOLFOX in this setting as long as the patie...
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