Topics:
Breast Cancer • Medical Oncology
What would be your choice of adjuvant chemotherapy for a healthy patient with localized triple negative breast cancer who is not a candidate for anthracycline and has severe neuropathy?
Patient received anthracycline and paclitaxel for HR+ breast cancer in the past.
Answer from: Medical Oncologist at Academic Institution
I probably would offer adjuvant chemotherapy with CMF. This is a regimen we don't use anymore, but it clearly improves outcome compared to no chemotherapy.CMF as adjuvant chemotherapy in triple negative BCThis case is described as not being a candidate for anthracyclines and with severe neuropathy, ...
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Answer from: Medical Oncologist at Academic Institution
I'm assuming that this patient had adjuvant treatment with an anthracycline and paclitaxel for her primary treatment, and she developed a local invasive recurrence. I too would go with CMF.