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What would be your radiotherapy plan for a patient with recurrent GBM (WHO grade 4, IDH wild-type) s/p 2 prior resections with no prior radiation?

Patient refused RT before but is now willing to consider it. The patient lives 3 hours away from the radiotherapy center. Is there a role for hypofractionated radiation in patients with good PS under the age of 60?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Arizona
Answered on

The scenario described in this clinical case is not uncommon. I have had patients who either live several hours away from our center or were unwilling to receive the Stupp protocol of 60 Gy in 6 weeks and were successfully treated with 3 weeks of hypofractionated RT (HFRT). HFRT over 1–3 weeks (25 G...

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