When do you consider neoadjuvant chemotherapy prior to definitive chemoradiation for cervical cancer?

Topics: Radiation Oncology • Gynecologic Cancers

Would organ invasion (bladder/rectum), size, feasibility of T&O, or size of nodes push you toward neoadjuvant chemotherapy?

Answer from: Radiation Oncologist at Academic Institution

Although we are occassionally referred patients for "consolidation" of loco-regional disease after favorable responses to chemotherapy for stage IVB disease, we very rarely give neoadjuvant chemotherapy for patients with stage I-IVA cancers with nodal disease confined to the pelvis and PA regions. E...

Comments

Radiation Oncologist at Maimonides Medical Center
Thanks so much for the informative and comprehensi...

Radiation Oncologist at The Center for Cancer Care
Thank you for the detailed and thoughtful response...

Answer from: Radiation Oncologist at Community Practice

Tumor size or local extensions to bladder or rectum are not indication for NACT as it would delay local treatment with no improvement in outcome

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