When do you consider neoadjuvant chemotherapy prior to definitive chemoradiation for cervical cancer?

Although we are occassionally referred patients for "consolidation" of loco-regional disease after favorable responses to chemotherapy for stage IVB disease, we very rarely give neoadjuvant chemotherapy for patients with stage I-IVA cancers with nodal disease confined to the pelvis and PA regions. E...

Tumor size or local extensions to bladder or rectum are not indication for NACT as it would delay local treatment with no improvement in outcome