When do you recommend PMRT for individuals with spindle cell carcinoma of the breast?
Do you use the typical indications for PMRT (nodal status, size of primary, LVSI, age, etc)? Or, do you recommended PMRT more frequently (even in the node-negative setting) given the histology is potentially more similar to a sarcoma than a carcinoma?"
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on
These cancers are in a broad category of metaplastic cancer of the breast. They are triple negative but are not chemoresponsive like ductal triple negative breast cancer and tend to have poor outcome. Our threhold for adding RT is lower in these patients.
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