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When do you trial pyridostigmine in a patient with suspected myasthenia gravis?

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Do you consider outpatient pyridostigmine trials to be a sufficient substitute for edrophonium or neostigmine testing in most patients with suspected MG?

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1 Answer
Mednet Member
Mednet Member
Neurology · Yale
Answered on

I usually try it very early on if I have a reasonable suspicion. Compared to the tensilon test and even the neostigmine test, a diagnostic trial of pyridostigmine is safer and more resource-efficient. Diagnostic trials of pyridostigmine are not particularly evidence-based, nor is treatment, but this...

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