When in the treatment of OA do you think it is optimal to offer LDRT?

Many guidelines continue to list LDRT as a non-primary/secondary intervention; do you wait to offer LDRT until after trial of conventional primary interventions such as anti-inflammatories, CSI, etc? Is there optimal timing for incorporation of LDRT? This question is part of our collaboration with ASTRO 2025 to highlight impactful trial data from this year's meeting. This question is inspired by the Clinical Trials Session Presentation "Clinical Effectiveness of Single Course Low-Dose Radiation Therapy in Knee Osteoarthritis: Short-term Results from the Randomized, Sham-Controlled Trial" by Dr. Byoung Hyuck Kim.