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When MGUS is suspected in a patient with one risk factor and no evidence of end-organ damage, what additional workup should be done, if any?

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Mednet Member
Mednet Member
Medical Oncology · Los Angeles VA Medical Center

My approach applies only for the scenario of thinking about monoclonal gammopathy -> myeloma spectrum. Monoclonal gammopathy -> amyloidosis or MGRS/MGNS, etc. I think of quite differently.

Our VA pathways and other organizations have advocated for bone marrow biopsy in this situation. For example, in...

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When MGUS is suspected in a patient with one risk factor and no evidence of end-organ damage, what additional workup should be done, if any? | Mednet