When re-irradiating the spinal cord, what do you use as a guideline for the interval between treatment and the amount of tolerance theoretically "regained"?

Perhaps the most commonly used estimate is that the spinal cord “heals” 25% of the previously delivered dose six months after completing radiation. While this statement didn’t originate with the QUANTEC paper by Kirkpatrick et al. on the subject, it is explicitly stated there, and the paper is a goo...

Data appear to be limited. You might consider the paper published by Nieder, et al., where in 'the risk of radiation myelopathy appears small after < or =135.5 Gy(2) when the interval is not shorter than 6 months and the dose of each course is < or =98 Gy(2)' They used an alpha-beta ratio of 2 for t...

I would suggest 6 months—see Dr. Kirkpatrick’s paper in the Quantec red journal issue