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When starting stress dose steroids for patient with primary adrenal insufficiency, how do you decide whether to start hydrocortisone 100 mg every 8 hours versus 50 mg every 6 hours?

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When starting stress dose steroids for patient with primary adrenal insufficiency, do you recommend hydrocortisone 100 mg every 8 hours or 50 mg every 6 hours?

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Endocrinology · Michigan State University College of Human Medicine
Answered on

Stress doses of steroids in patients with primary adrenal insufficiency depend on the anticipated stress. The dose of steroids can be doubled or tripled depending on the stress. For example, in cases of maximal stress such as major surgery, the dose can be similar to the dose used for an adrenal cri...

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