Topics:
Radiation Oncology • Genitourinary Cancers
When treating a patient definitively for high risk prostate cancer, how would you interpret the interval development of sclerotic bone lesions that appeared during neoadjuvant ADT?
Could these be subclinical metastases that responded to ADT? Do they require further workup?
Answer from: Radiation Oncologist at Community Practice
It most likely reflects treated metastatic disease but can be very difficult to prove, as bx yield is low since it has been treated. Would not change management and complete planned treatment. Stampede also showed benefit of local RT for limited bone mets
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